SNP discovery and molecular evolution in Anopheles gambiae, with special emphasis on innate immune system

BMC Genomics

Table 1 McDonald and Kreitman test results in immune and non immune related genes

A: Between A. arabiensis and M form for immune related genes
	Non synonymous	Synonymous	Ratios
Interspecific fixed divergences	36	63	0.571
Intraspecific polymorphisms	344	905	0.380
Ratios	0.104	0.070	P = 0.081
B: Between A. arabiensis and S form for immune related genes
	Non synonymous	Synonymous	Ratios
Interspecific fixed divergences	24	37	0.649
Intraspecific polymorphisms	421	1171	0.360
Ratios	0.057	0.032	P = 0.038
C: Between A. arabiensis and M form for non immune related genes
	Non synonymous	Synonymous	Ratios
Interspecific fixed divergences	16	55	0.290
Intraspecific polymorphisms	151	675	0.224
Ratios	0.106	0.081	P = 0.426
D: Between A. arabiensis and S form for non immune related genes
	Non synonymous	Synonymous	Ratios
Interspecific fixed divergences	14	49	0.286
Intraspecific polymorphisms	192	798	0.241
Ratios	0.073	0.061	P = 0.622

SNPs were counted for the groups of genes (immune related or non immune related genes) within species (Intraspecific polymorphisms) or between species (Interspecific fixed divergences). The probability (P) is calculated using a 2-tailed Fisher's exact test.

ISSN: 1471-2164