Table 2 Motifs previously identified in other genes found in the DRB1-e2

Polypurine tract

5'-RRRRR(RRR)-3'

88–95

121–125^a

178–184

246–250

Polypyrimidine tract

5'-YYYYY-3'

5–10

36–41

Immunoglobulin heavy chain class switch repeat

5'-GAGCT-3'

141–145

DRB1*0328

248–252

DRB1*0452

5'-TGGGG-3'

145–149

DRB1*07

Deletion hotspot consensus

5'-TGAAGA-3'

37–42^b

5'-TGRRKM-3'

145–150

DRB1*07

250–255^b

Chi-like sequence

5'-GCTGGGG-3'

143–149

DRB1*07

5'-CTGG-3'

144–147^b

DRB1*07

167–170^b

DRB1*0705

176–179

Topoisomerase I consensus cleavage site

5'-CTY-3'

38–40

251–253

DRB1*0423, *0452

5'-GTY-3'

4–6

31–33

47–49^b

108–110^b

114–116^b

171–173^b

183–185^b

213–215^b

231–233^b

DNA polymerase a pause site core sequence

5'-GAG-3'

51–53

DRB1*0439

121–123

246–251 (2×)

268–270

5'-ACG-3'

2–4

115–117

116–118^b

Deletion hotspot

5'-YYYTG-3'

7–11

177–181^b

DRB1*0705

187–191

DRB1*1374