Table 2 Quantitative RT-PCR validation of human gene transcripts.
Gene symbol | Gene name | Fold Change | |
|---|---|---|---|
|  |  | MDM+Lm/MDM Ratio&occurrences | 2-ΔΔCT |
Chemokine activity | |||
IL-8 | Interleukin 8 | 7.5 (15:2) | 20 |
CXCL3 | Chemokine (C-X-C motif) ligand 3 | 8 (8:1) | 11.67 |
CXCL9 | Chemokine (C-X-C motif) ligand 9 | 0.25 (2:8) | 0.19 |
CXCL10 | Chemokine (C-X-C motif) ligand 10 | 0.25 (0:4) | 0.15 |
Cytoskeleton | |||
GSN | Gelsolin (amyloidosis, Finnish type) | 0.44 (12:27) | 0.29 |
ADFP | Adipose differentiation-related protein | 13 (13:1) | 2.43 |
ACTG1 | Actin, gamma 1 | 0.62 (5:8) | 0.40 |
Extra-cellular space | |||
MMP12 | Matrix metallopeptidase 12 (macrophage elastase) | 0.46 (2:9) | 0.22 |
PTPNS1 | Protein tyrosine phosphatase, non-receptor type S1 | 0.12 (1:8) | 0.57 |
FN1 | Fibronectin 1 | 0.05 (1:19) | 0.28 |
Inflammatory Response | |||
FCGR3 | Fc fragment of IgG, low affinity IIIb, receptor (CD16) | 0.22 (2:9) | 0.22 |
C5R1 | complement component 5 receptor 1 (C5a ligand) | 0.21 (3:14) | 0.65 |
CHIT1 | chitinase 1 (chitotriosidase) | 0.33 (0:3) | 0.86 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 8 (8:1) | 0.66 |
Membrane-associated protein | |||
AP2S1 | Adaptor-related protein complex 2, sigma 1 subunit | 0.50 (1:2) | 0.38 |
GPNMB | Glycoprotein (transmembrane) nmb | 0.81 (36:44 | 1.07 |
CD164 | CD164 molecule, sialomucin | 0.16 (1:6) | 0.79 |
SCARB2 | Scavenger receptor class B, member 2 | 0.25 (0:4) | 0.66 |
Processing, folding and targeting | |||
SRP9 | signal recognition particle | 0.16 (1:6) | 0.49 |
RPL13A | Ribosomal protein L13a | 0.44 (12:27) | 0.28 |
LGMN | Legumain | 7 (7:1) | 0.90 |
HSPA8 | Heat shock 70 kDa protein 8 | 0,33 (5:15) | 0.58 |
Response to stress | |||
SOD2 | Superoxide dismutase 2, mitochondrial | 2.5 (15:6) | 2.17 |
GLRX | Glutaredoxin (thioltransferase) | 0.66 (4:6) | 0.78 |
MX1 | Myxovirus resistance1, IFN-inducible protein p78 | 3 (9:3) | 2.21 |
P4HB | Procollagen-proline, 2-oxoglutarate 4-dioxygenase | 0.27 (3:11) | 0.63 |
Signal transduction events | |||
S100A8 | S100 calcium binding protein A8 (calgranulin A) | 0.36 (18:50) | 0.15 |
SH3BGRL3 | SH3 domain binding glutamic acid-rich protein-like 3 | 0.12 (0:8) | 0.44 |
MAPKAPK3 | Mitogen-activated protein kinase-activated protein kinase3 | 0.11 (0:9) | 0.56 |
ILK | Integrin-linked kinase | 1 (4:4) | 0.64 |
PLCB2 | Phospholipase C, beta 2 | 0.16 (0:6) | 0.40 |
PTPRC | Protein tyrosine phosphatase, receptor type, C | 0.5 (3:6) | 0.41 |
SH3BP2 | SH3-domain binding protein 2 | 0.44 (4:9) | 0.66 |
Transcription-related activity | |||
IRF1 | Interferon regulatory factor 1 | 0.28 (2:7) | 0.50 |
IRF7 | interferon regulatory factor 7 | 8 (8:1) | 1.37 |
STAT1 | Signal transducer and activator of transcription 1 | 0.22 (4:18) | 0.63 |
DDX3X | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 | 0.81 (9:11) | 0.66 |
CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 12 (12:1) | 0.81 |
EGR1 | Early growth response 1 | 4.5 (18:4) | 0.61 |
Lysosomal-associated protein | |||
CTSS | Cathepsin S | 0.15 (3:20) | 0.58 |
LAPTM5 | Lysosomal-associated protein | 1 (17:17) | 0.52 |
IFI30 | Interferon, gamma-inducible protein 30 | 0.58 (67:115) | 0.53 |