Figure 6From: Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growthLantibiotic prodiction by B. longum DJO10A. (A) Organization of the lantibiotic encoding unique region 12 of B. longum DJO10A and the corresponding genome locations in strains NCC2705 and DJO10A-JH1. The A or B designator following IS30 refer to unique classes of IS30 elements that are only found at this location in the genome. The ' designator indicates a fragmented IS30 element. (B) Pulsed Field Gel Electrophoresis (PFGE) analysis of Xba I-digested total DNA from B. longum DJO10A and its fermentation adapted isolate, DJO10A-JH1. White arrows indicate bands missing from strain DJO10A-JH1. (C) Bioassay for lantibiotic production by B. longum DJO10A with strains DJO10A and DJO10A-JH1 as indicator bacteria.Back to article page