Genomic Organization of Zebrafish microRNAs

BMC Genomics

Table 1 Newly Identified Zebrafish miRNAs.

Name	Chromosome	Conserved	Name	Chromosome	Conserved
miR-466a-3p	2	mmu	miR-467a*-9	8	mmu
miR-466b-5p	24	mmu	miR-467d*	11	mmu
miR-466c-1	12	mmu	miR-467e*-1	16	mmu
miR-466c-2	12	mmu	miR-467e*-2	10	mmu
miR-466d	17	mmu, fru	miR-469a	16	mmu
miR-466h-1	1	mmu, fru	miR-705	9	mmu
miR-466h-2	1	mmu, fru	miR-710	17	mmu
miR-466h-3	1	mmu, fru	miR-718	14	mmu
miR-466h-4	1	mmu, fru	miR-741	7	mmu
miR-466h-5	24	mmu, fru	miR-743b-5p	25	mmu
miR-467a*-1	13	mmu	miR-758	18	mmu
miR-467a*-2	4	mmu	miR-759	8	mmu
miR-467a*-3	21	mmu	miR-760	8	mmu, fru
miR-467a*-4	12	mmu	miR-872	3	mmu
miR-467a*-5	18	mmu	miR-876-3p	24	mmu
miR-467a*-6	12	mmu	miR-876-5p	20	mmu
miR-467a*-7	12	mmu	miR-883b-3p	3	mmu
miR-467a*-8	24	mmu

Conserved mouse miRNA sequences within the microRNA Registry were used to conduct BLAST searches of the existing zebrafish and fugu genomes. Candidate sequences (>80% sequency identity) were further analyzed using mFold and MiRscan. For those sequences that matched miRNAs from other vertebrate species, the same numbering system was applied resulting in the miRNAs listed above. miRNAs with an sterisk indicate that both strands of the dsRNA precursor are packaged into RNA Induced Silencing Complexes (RISCs). (fru: fugu, mmu: mouse)

ISSN: 1471-2164