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Table 6 Distribution of SIDER retroposons among differentially expressed Leishmania spp. transcripts.

From: Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species

  Differentially Expressed Transcriptsa Genomic Distributionb
Species Life Stage SIDER1% SIDER2% SIDER1% SIDER2%
L. major amastigote 23.9 18.3 11.6 15.0
  promastigote 10.6 11.6   
L. infantum amastigote 14.1 11.9 9.4 15.8
  promastigote 8.4 12.4   
  1. a As determined by the DNA microarray experiments (this study).
  2. b Refined species-specific hidden Markov model profiles were used to determine the genomic distribution of two SIDER families in L. infantum and L. major ([46]; Smith et al. unpublished)). Values represent the proportion of annotated coding sequences that potentially harbor at least one SIDER element in their 3'UTR. The percentage of SIDERs in differentially expressed transcripts is compared with the genomic distribution of SIDERs.