SIDER2 sequences are found in linear inverted DNA amplicons of Leishmania. (A) Schematic representation showing the location of the repeated sequences RS1, RS2 and RS3 in the M210 and M230 L. major amplicons and in the chromosome source (depicted according to data shown in reference ). The location and orientation of the RS1, RS2 and RS3 repeats are indicated by arrows. The rearrangement points are indicated by discontinuous, vertical lines. The extent and orientation of the inversions are indicated by horizontal arrows. The drawing is not to scale. (B) Alignment of RS1 and LiSIDER2-32-661708r sequences. Symbol (:) indicates identical bases in both sequences. Gaps (-) were introduced to maximize the alignment.