Figure 1

Length distribution of siRNAs. The siRNAs were obtained by high-throughput sequencing of mixed stage C. elegans populations from two library sources (Lee et al., 2006; Ruby et al., 2006). The height of the bars indicates the number of siRNAs for the respective length. The shaded portion of the histograms indicates the number of siRNAs with an mRNA sequence match. A) Length distribution of all 7136 available short RNA sequences from C. elegans available from the two library sources. The length of sequences ranged from 12- to 37 nucleotides. A total of 4024 siRNA sequences matched with an mRNA sequence from the two library sources. B) Length distribution of siRNAs from the library reported in Lee et al., 2006. C) Length distribution of siRNAs from the library reported in Ruby et al., 2006.