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Table 1 Progression of disease and mortality in VEEV infected mice.

From: Venezuelan equine encephalitis virus infection causes modulation of inflammatory and immune response genes in mouse brain

Disease Progression Day(s) Post Infection
  0 1 2 3 4 5 6 7 8 9
Roughening of Fur 0 0 5 9 9 8 5 1 1 -
Hunched Posture/Lethargic/Shivering 0 0 0 0 9 8 5 1 1 -
Hind Limb Paralysis 0 0 0 0 1 8 5 1 1 -
Death 0 0 0 0 0 1 3 4 0 1
Total died/Total No. 0/9 0/9 0/9 0/9 0/9 1/9 4/9 8/9 8/9 9/9
% Mortality 0 0 0 0 0 11.1 44.4 88.8 88.8 100
MST (Day) 6.66
  1. Mice were infected with 1000 pfu of V3000 in left rear foot pad at day 0 and were monitored for the clinical symptoms of disease thereafter. All the animals exhibited hind limb paralysis, a hallmark of VEEV infection and succumbed to disease by day 9 post infection. Mortality was 100% with a mean survival time of 6.6 days.
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