Table 4 Genes involved in apoptotic response in VEEV infected mice brain.

Mm.3336

RIKEN cDNA 1110007C09 gene (1110007C09Rik)

2.66 ± 1.63

3.68 ± 1.14

6.81 ± 4.35

5.22 ± 0.66

Mm.277585

amyloid beta (A4) precursor protein (App)

2.50 ± 0.48

2.54 ± 0.59

4.05 ± 1.20

2.87 ± 0.42

Mm.84073

Bcl2-associated athanogene 3 (Bag3)

2.63 ± 0.59

3.30 ± 0.43

4.61 ± 2.37

4.23 ± 0.18

Mm.29820

BCL2/adenovirus E1B 19kDa-interacting protein 3-like (Bnip3l)

1.96 ± 0.11

2.52 ± 0.04

3.88 ± 2.19

3.07 ± 0.14

Mm.290908

baculoviral IAP repeat-containing 6 (Birc6), mRNA.

1.94 ± 0.33

2.15 ± 0.22

2.54 ± 0.93

2.18 ± 0.04

Mm.283714

sialophorin (Spn), mRNA.

1.99 ± 0.14

2.50 ± 0.19

2.87 ± 1.63

2.25 ± 0.24

Mm.2381

amyloid beta (A4) precursor-like protein 1 (Aplp1),

NE

1.90 ± 0.06

3.70 ± 1.15

2.27 ± 0.14

Mm.200608

Clusterin (Clu)

NE

1.74 ± 0.13

4.03 ± 1.54

2.45 ± 0.37

Mm.136224

interferon induced with helicase C domain 1 (Ifih1)

NE

3.59/-

5.21 ± 1.05

4.18 ± 0.31

Mm.4266

integral membrane protein 2B (Itm2b)

NE

1.55 ± 0.20

2.43 ± 0.95

2.46 ± 0.54

Mm.2326

macrophage migration inhibitory factor (Mif)

NE

1.08 ± 0.17

2.25 ± 0.53

2.06 ± 0.07

Mm.277518

Monocyte to macrophage differentiation-associated (Mmd)

NE

0.59 ± 0.04

2.33 ± 0.45

1.64 ± 0.18

Mm.347546

Inositol 1,3,4-triphosphate 5/6 kinase

NE

1.94 ± 0.02

0.95 ± 0.05

1.83 ± 0.02

Mm.285322

mitochondrial carrier homolog 1 (C. elegans) (Mtch1)

NE

0.95 ± 0.01

2.08 ± 0.35

1.77 ± 0.23

Mm.687

Ras homolog gene family, member B (Rhob)

NE

1.17 ± 0.03

2.48 ± 0.87

1.59 ± 0.15

Mm.379457

Valosin containing protein (Vcp)

NE

1.68 ± 0.15

2.04 ± 0.77

1.80 ± 0.17

Mm.6826

Apoptosis-associated tyrosine kinase (Aatk)

NE

NE

1.65 ± 0.07

1.20 ± 0.43

Mm.223689

Bifunctional apoptosis regulator (Bfar)

NE

NE

1.83 ± 0.58

1.70 ± 0.08

Mm.130832

caspase recruitment domain family, member 14 (Card14)

NE

NE

3.23 ± 1.52

2.69 ± 0.08

Mm.29028

Death associated protein 3 (Dap3)

NE

NE

1.87 ± 0.14

0.96 ± 0.03

Mm.280594

Death effector domain-containing DNA binding protein 2 (Dedd2)

NE

NE

1.79 ± 0.66

1.92 ± 0.09

Mm.379461

eukaryotic translation initiation factor 5A (Eif5a)

NE

NE

2.61 ± 0.49

1.92 ± 0.14

Mm.342392

engulfment and cell motility 1, ced-12 homolog (C. elegans) (Elmo1), transcript variant 2

NE

NE

1.74 ± 0.21

1.41 ± 0.08

Mm.39760

Fas apoptotic inhibitory molecule 2 (Faim2)

NE

NE

2.85 ± 1.23

2.44 ± 0.12

Mm.281298

growth arrest and DNA-damage-inducible 45 gamma (Gadd45g)

NE

NE

3.16 ± 0.21

2.12 ± 0.05

Mm.15510

granzyme A (Gzma)

NE

NE

1.27 ± 0.41

1.94 ± 0.26

Mm.2720

Mitogen activated protein kinase 8 interacting protein 1 (Mapk8ip1)

NE

NE

2.25 ± 0.75

1.16 ± 0.19

Mm.1639

Myeloid cell leukemia sequence 1 (Mcl1)

NE

NE

1.83 ± 0.18

1.56 ± 0.09

Mm.204876

nucleolar protein 3 (apoptosis repressor with CARD domain) (Nol3)

NE

NE

2.02 ± 0.52

1.84 ± 0.09

Mm.24163

PYD and CARD domain containing (Pycard)

NE

NE

1.82 ± 0.17

1.38 ± 0.18

Mm.276325

superoxide dismutase 1, soluble (Sod1)

NE

NE

1.74 ± 0.22

1.54 ± 0.24

Mm.200792

tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21)

NE

NE

2.37 ± 0.84

1.40 ± 0.17

Mm.1894

CD1d1 antigen (Cd1d1)

NE

NE

NE

1.56 ± 0.01

Mm.217764

phosphoglucomutase 2 (Pgm2)/Itgb3bp

NE

NE

NE

1.63 ± 0.11

Mm.312628

Serine (or cysteine) proteinase inhibitor, clade A, member 3G (Serpina3g)

NE

NE

NE

2.83 ± 0.18

Mm.218473

tumor differentially expressed 1 (Tde1)/Serinc3

NE

NE

NE

1.94 ± 0.01

Mm.338613

forkhead box O3a (Foxo3a)

1.92 ± 0.17

NE

2.26 ± 1.08

1.57 ± 0.03

Mm.22216

TSC22 domain family 3 (Tcs22d3)

NE

1.63 ± 0.20

NE

NE

Mm.1360

growth arrest and DNA-damage-inducible 45 beta (Gadd45b)

NE

2.00 ± 0.33

NE

1.85 ± 0.03

Mm.329277

ubiquitin specific peptidase 14 (Usp14)/Thoc1

NE

1.90 ± 0.21

NE

2.02 ± 0.18

Mm.347406

CCAAT/enhancer binding protein (C/EBP), beta (Cebpb)

NE

NE

2.01 ± 0.17

NE

Mm.150

Fc receptor, IgG, high affinity 1(Fcgr1)

NE

NE

2.26 ± 0.26

NE

Mm.292100

fibrinogen-like protein 2 (Fgl2)

NE

NE

1.90 ± 0.27

NE

Mm.368515

myc-like oncogene, s-myc protein (Mycs)

NE

NE

3.11 ± 0.05

NE