Figure 2

Percent identity plot of the chromosomal regions encompassing the Jmjd6 locus in vertebrate species. The genomic regions of eight vertebrate species identified as putative Jmjd6 orthologous loci were aligned with the mouse Jmjd6 locus and its neighbouring genes using PipMaker. Green, blue and yellow overlays highlight the conservation of the annotated exons/coding sequences of the individual genes found in the reference sequence. The orange overlay indicates conserved sequences of the first exons of the Jmjd6 and 1110005A03Rik genes and sequences outside of the coding elements. The red overlay marks a high-scoring segment in all analysed mammalian species supporting the presence of at least one additional exon (No. 5) that is not included in the current Ensembl gene annotation (build 44). Transcriptional orientations of the genes, their exons, UTRs, repetitive elements, and CpG islands are in the symbol key at the figure bottom.