Figure 3

Dendrogram and Domain Architecture for RAWUL domain containing proteins. The sequences are named as described in Figure 1. Vitis vinifera (Vitvi) sequences were included to construct the dendrogram. The main families (PRC1 Ring and WDR48-p80) and subfamilies (Bmi1/Mel18 and Ring1A/B) are indicated by coloured dotted lines, as in Figure 1. Only a representative set of sequences was labelled. The scale bar shows the average number of amino acid substitutions per site (0.1). The main bootstrap values for PRC1 Ring family classification are indicated. Schematics of domain architecture are represented with the localization of the RAWUL, Ring domains and WD40 repeats according to this analysis, Pfam [91] and REP web servers [92], respectively.