Skip to main content

Table 3 Indirect hypothesis category of yeast genes shown by microarray analysis to be affected by berenil treatment

From: Microarray analysis of the in vivo sequence preferences of a minor groove binding drug

ORF

Gene

Ratio

Function

Process

YOL052C-A

DDR2

-2.44

response to stress

unknown

YGR088W

CTT1

-2.35

response to stress

catalase activity

YBR072W

HSP26

-2.32

response to stress

chaperone activity

YML100W

TSL1

-2.17

response to stress

enzyme regulator activity

YCR021C

HSP30

-2.17

response to stress

heat shock protein activity

YFL014W

HSP12

-1.93

response to oxidative stress

heat shock protein activity

YMR250W

GAD1

-1.66

response to oxidative stress

glutamate decarboxylase

YMR169C

ALD3

-1.64

response to stress

aldehyde dehydrogenase

YNL160W

YGP1

-1.42

response to stress

unknown

YDR258C

HSP78

-1.42

response to stress

chaperone activity

YDR074W

TPS2

-1.28

response to stress

trehalose phosphatase

YKL026C

GPX1

-1.24

response to oxidative stress

glutathione peroxidase

YLL026W

HSP104

-1.18

response to stress

heat shock protein activity

YLL039C

UBI4

-1.18

response to stress

protein tagging activity

  1. Genes hypothesized to be indirectly affected by berenil treatment are listed with their expression ratios (log2 transformed treated to untreated) and functions, if known.