Immunity related genes in dipterans share common enrichment of AT-rich motifs in their 5' regulatory regions that are potentially involved in nucleosome formation

Table 15 Overrepresentation of AT rich motifs is specific of immunity-induced genes

Organism	Group of genes	AA score	TA score	AT score	AAA score	ATAA score
Anopheles gambiae	Immunity induced	20.99	14.39	13.25	6.11	11.26
	Down-regulated	---	---	---	0.77	---
	Non-modified	---	---	---	---	---
	Random genes	0.42	---	---	2.51	---
	Artificial	---	12.11	---	---	---
Drosophila melanogaster	Immunity induced	37.43	15.64	14.80	22.30	14.21
	Down-regulated	---	2.25	3.27	---	2.2
	Non-modified	2.97	---	0.11	1.42	---
	Random genes	1.9	---	---	0.7	---
	Artificial	---	---	---	---	---

The overrepresented motifs are specific of immunity-related gene promoters of Anopheles gambiae and Drosophila melanogaster.

ISSN: 1471-2164