Figure 1

Global Gene Ontology mapping of the selenite response in S. cerevisiae. (A): The gene ontology categories with levels of expression significantly changed by selenite were identified by T-profiler [22]. The graph represents only the most significant functional categories, as a function of time. More complete T-profiler results are available in additional file 3. The color code is as follows: black: E-value > 0.05 (non significant variation); red: E-value < 0.05 and t-value > 0 (positive significant variation); green: E-value < 0.05 and t-value < 0 (negative significant variation). (B): Gene expression patterns for the functional categories discussed further in the text. Wild-type cells were treated with selenite and gene expression was evaluated by microarray analyses at different time points, using untreated cells as a reference. Note that the lists of genes represented here are not exhaustive and represent a sample of the genes present in these GO categories. More complete information can be found in additional file 1.