| WT1 | EGR1 | SP1 | SP2 | AP2 | GATA1 |
---|
Total # of TFBS
a
|
47
|
31
|
50
|
12
|
16
|
18
|
Primates
| Â | Â | Â | Â | Â | Â |
Chimpanzee | 36 (77%) | 28 (90%) | 35 (70%) | 11 (92%) | 11 (69%) | 13 (72%) |
Macaque | 28 (60%) | 25 (81%) | 27 (54%) | 6 (50%) | 9 (56%) | 8 (44%) |
Primate % conserved
b
|
68%
|
85%
|
62%
|
71%
|
63%
|
58%
|
Rodents
| Â | Â | Â | Â | Â | Â |
Mouse | 6 (13%) | 9 (29%) | 12 (24%) | 1 (8%) | 2 (13%) | 3 (17%) |
Rat | 8 (17%) | 8 (26%) | 10 (20%) | 0 (0%) | 1 (6%) | 2 (11%) |
Rodent % conserved
c
|
15%
|
26%
|
22%
|
4%
|
9%
|
14%
|
Marsupials
| Â | Â | Â | Â | Â | Â |
Opossum | 3 | 6 | 6 | 0 | 1 | 0 |
% conserved
|
6%
|
19%
|
12%
|
0%
|
6%
|
0%
|
- a Total # of TFBS = The total number of TFBS predicted by MatIspector [75] based on TFBS in human promoters of 11 genes. Numbers of evolutionary conserved TFBS shared between human and each species are shown below (percent of sites conserved shown in parenthesis).
- b Primate % conserved = Average number of chimpanzee and macaque evolutionary conserved TFBS divided by the total number of TFBS predicted for that particular TF.
- c Rodent % conserved = Average number of mouse and rat evolutionary conserved TFBS divided by the total number of TFBS for that particular TF.