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Figure 4 | BMC Genomics

Figure 4

From: Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer

Figure 4

Protein-level downregulation of eIF4G1 in rapamycin-treated BT-474 cells and in Ly294002-treated SK-BR-3 cells. The breast cancer cells were treated with 100 nM rapamycin and 50 μM Ly294002 for 24 hours and the protein expression of eIF4G1 was detected by Western immunoblotting. The plus (+) sign indicates the inhibitor-treated sample and the minus (-) sign the non-treated sample. A) Rapamycin and B) Ly294002 downregulated eIF4G1 expression at protein level in BT-474 and SK-BR-3 cells, respectively. Beta-actin was used as a loading control.

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