Figure 4
From: Genome-wide analysis of alternative promoters of human genes using a custom promoter tiling array
Shown here are the first four exons of the gene NCOA7, spanning a region of roughly 32 kb (A). Exon 3 is spliced out of the transcript initiated at Exon 1, but Exon 4 is common to both transcripts. The ChIP-chip microarray analysis indicated that the first promoter is inactive in the control experiment, but is activated with E2 treatment at a low level, a result that is verified by qRT-PCR results (B). The second promoter was predicted to be active at a low level with and without E2 treatment, which again was verified (C). Error bars indicate standard errors from the mean for three replicates.