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Figure 4 | BMC Genomics

Figure 4

From: Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project

Figure 4

No correlation between HML-2 provirus activity and HML-2 Gag and Env antibodies in GCT patients. Relative cloning frequencies of gag-derived cDNAs from various HML-2 loci in malignant and pathologic testicular tissues are given. Only active HML-2 loci have been included. Results for tissue samples (GC1, 5, 6, 14, 15) from patients with antibodies against Gag and Env (αGag+/αEnv+) are shown as red bars. Yellow bars denote results for tissue samples (GC4, 8) from patients with Env but without Gag antibodies (αGag-/αEnv+). Green bars denote results for control tissue samples (GC3, 9, 11) from patients with neither Gag nor Env antibodies (αGag-/αEnv-). Note that none of the HML-2 loci appears exclusively expressed in all Gag and/or Env antibody-positive samples but not in antibody-negative control samples.

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