Individual | H1 | H2 | H3 | H4 | H5 | H6 | H7 | H8 | H9 | H10 | Genotype model | χ2-value | p-value |
---|
S9 | 19 | 2 | | | 3 | | | | | | 1/1/2/5 | 8.25 | 0.02 |
S25 | | | | 21 | | | | 27 | | |
4/4/8/8
| 0.75 | 0.39 |
S50 | 18 | | 3 | | | 3 | | | | | 1/1/3/6 | 6.00 | 0.05 |
S73 | 18 | | | | | | | 14 | | |
1/1/8/8
| 0.50 | 0.48 |
S83 | 26 | | | | 2 | | | | | | 1/1/1/5 | 4.76 | 0.03 |
S89 | | | | | 7 | | 2 | 14 | | |
8/8/5/7
| 3.26 | 0.20 |
S93 | | | | | | | | 26 | | |
8/8/8/8
| 0 | 1 |
B1 | | | | | 7 | | | 17 | | |
8/8/8/5
| 0.22 | 0.64 |
B4 | | | | | 4 | | | 19 | | |
8/8/8/5
| 0.71 | 0.40 |
B26 | | | | | | | | 24 | | | | 0 | 1 |
B30 | | | | | 79 | | | | | |
5/5/5/5
| 0 | 1 |
B37 | 7 | | | | | | | 16 | | |
8/8/8/1
| 0.36 | 0.55 |
B43 | 28 | | 2 | | | | | | | | 1/1/1/3 | 5.38 | 0.02 |
B52 | 9 | | | | | | | 14 | | |
1/1/8/8
1/8/8/8
| 1.09 or 2.45 | 0.30 0.12 |
B63 | | | | | 2 | | | 17 | 2 | 8 | 5/8/9/10 | 20.79 | 0.0001 |
B75 | | | | | 2 | | | 9 | | 13 |
10/10/5/8
| 4.25 | 0.12 |
B80 | 10 | | | | 12 | | | | | |
1/1/5/5
| 0.18 | 0.67 |
B86 | | | | | 5 | | | 19 | | |
8/8/8/5
| 0.22 | 0.64 |
B108 | 20 | | | | 3 | | | | | |
1/1/1/5
| 1.75 | 0.19 |
- For nineteen individuals, the number of clones obtained per individual for each of the ten haplotypes (Table 4) and the resulting genotype model are shown. For each genotype model, the goodness of fit (chi-square) and the p-values for the deviation of the number of observed clones from the expectation based on the genotype model are calculated. Genotype models which do not significantly deviate from the observed haplotype distribution are shown in bold (significance level: 5%). It is assumed that haplotype frequencies deviate χ2 distributed from the genotype model, with # of different alleles -1 degrees of freedom. In the first row of Table 5, the χ2-value is calculated as follows: . The p-value represents the probability of obtaining haplotype frequencies at least as extreme as the observed ones, given that the genotype model (null hypothesis) is true.