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Table 3 GO Term finder results for genes down-regulated by daunorubicin

From: Selective inhibition of yeast regulons by daunorubicin: A transcriptome-wide analysis

Gen Ontology Term clustering

Functional categories

GOID

GOID- associated functions

 

A

5975; 5996; 6006; 6007; 6066; 6067; 6082; 6090; 6094; 6096; 6113; 6766; 6767; 9056; 9063; 15980; 16051; 16052; 19318; 19319; 19320; 19752; 32787; 44248; 44262; 44275; 46164; 46165; 46364; 46365;

Alcohol and carbohydrate metabolism (including glycolysis). Vitamin and organic acid metabolism.

 

B

6091; 6099; 6100; 6519; 6520; 6536; 6537; 6807; 8652; 9064; 9084; 9308; 9309; 44271; 46356

Amino acid metabolic process. Tricarboxilic acid cycle.

 

Gene Clustering

Distribution among functional categories

Genes

Main gene functions

Number of genes

A>>B

GPD2; PDC1; PDC5; PCL7; UGP1; DAK1; GLO1; INO1; PGM2; MDH2; PSA1; GRE3; GCY1; GLK1; TPI1; HXK1; HXK2; PFK1; VID24; GND1; TKL1; PYC2; PGK1; TDH3; ENO1; ENO2; TDH1; TDH2; FBA1; GPM1

Glycolysis

30

A>B

AAH1; ADH1; ADH2; ADH5; ALD4; ALD6; AMS1; ARA1; AYR1; CTS1; EHT1; ERG10; ERG11; ERG26; ERG5; EXG1; FAS1; GPH1; GSY2; HOR2; LAP4; MDH1; PDH1; PEX11; PHO3; PRB1; RHR2; RIB1; RIB4; SCS7; SNO1; SNZ1; TPS2; TSL1

Alcohol, lipid and sterol metabolism

34

A ≈ B

AAT2; BAT2; CAR2; CHA1; COX20; GCV1; GCV2; GLY1; LSC2; MCR1; PPA2; QCR10; QCR2; RIP1; SRY1; UGA1

Amino acid metabolism. Respiration

16

A<B

ACO1; ARG1; ARG4; ARG8; ARO3; ARO4; CIT1; CPA1; CYT1; GDH1; GLT1; IDH1; IDH2; ILV5; MEP1; MEP3; MET6; URA2

Nitrogen compound (including amino acids) metabolism. Tricarboxilic acid cylce

18

No GO term

  

181