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Table 2 Selected genes enriched in α6+/MHCI-cells compared to α6+/MHCI+cells.

From: Transcriptional profiling of putative human epithelial stem cells

mRNAs enriched in HHFSC TNRC9 (1.5), PHLDA1 (1), WIF-1 (6.6), RIG (1.6), DPYSL2 (1.9), DPYSL3 (1.4), GPM6B (2.5), FZD1 (1.3), NFATC1 (1.7), FST (2.3), DCT (2.5).
mRNAs enriched in MHFSC LHX2 (5), TCF3 (1.5), WIF-1 (6.6), TRPS1 (2), BACH2 (1.1), LTBP1 (1.1), LTBP2 (1), ID2 (1), ID4 (1), DPYSL2 (1.9), DPYSL3 (1.4), GPR49 (2), GADD45G (1.2), ENPP1 (2.1), FBN2 (1), FOXC1 (1.7), VIM (1.7), DCT (2.5), MERTK (1.5), CRYM (1.5), CNR1 (1.4), SCD (2), TCF7 (1.1), CPE (1.9), EDNRB (2.8), AML1 (2.3), GPM6B(2.5), FGFR1 (2.5), CSPG2 (1.5), CSPG4 (2.1), NFATC1 (1.7), FYN (1.8), PRDM5 (1.5), ARG2 (1.4), MOX2 (2.9), DLX2 (1.8), ADAMTS5 (1.6), PHLDA1 (1), FZD7 (1.5), GUCY1B3 (1.5), TYR (2.1), COL1A2 (2), GPR64 (2.3), GSTM5 (1.2), PPAP2B (1.6), MITF (1.8), SNCAIP (1.2), SOX9 (1.9), MYH10 (1.1), MADH6 (1.6), INSIG1 (1.2), PLAT (1.4), PEG3 (2.8), NFIB (1.2), DAB2 (1.9), IGFBP5 (1.1), IGFBP7 (2.2), ITM2A (1.2), GFRA1 (1.5), ALCAM (1.6), BDNF (2.6), SDF1 (1.1), COL3A1 ((1), COL4A1 (1.9), COL4A2 (1.8), COL5A1 (1.1), COL6A1 (1.1), COL14A1 (1.3), HXB (1.3), ACTN1 (1.1), HPGD (1.1), APP (1.2), CTBP2 (1), MYO1B (1.1), SIAT4C (1.5), EFNB2 (1.3), EDG2 (1.2), CYP1B1 (3.5), PRLR (1.1), ALDH7A1 (1.1), DCAMKL1 (1.6), PAK3 (1.7).
TGFβ/BMP signaling MADH3 (1.3), MADH6 (1.6), MADHIP (1.5), FST (2.3), BMP5 (5.1), BMP8 (2), BMP10 (1.2). BMP15 (1.3), INHBC (1.8).
TGFβ/BMP-induced factors COL3A1 (1), COL4A1 (1.9), COL5A1 (1.1), COL6A1 (1.1), COL9A2 (1.6), COL11A1 (3.7), COL11A2 (1), COL14A1 (1.3), GPR56 (1.2), SOX4 (1.2), CLU (1.2), IQGAP1 (1.3), LMCD1 (2.7), SPRY4 (1.2), ITGB5 (1.1), LTBP1 (1), LTBP2 (1.1), GSN (1), PPAP2B (1.6), PEA15 (1.8), HEF1 (1.2), ID2 (1), ID4 (1), TGFB1l1 (1.3), FRZB (3.9), VCAM (1.2), FST (2), HXB (1.3), GSPG2 (2), AGC1 (1.5), THBS1 (2.3), APOE (1.1), MADH6 (1.6), NFATC1 (1.7), CKB (1.5), MMP9 (1.5), PLAUR (1.3), PLAT (1.4), APP (1.2), PTPRC (1.4), FZD1 (1.3), FYN (1.8), VAV1 (1.3), HCLS1 (1.1), TAL1 (1.1), LPL (1.3), BDNF (2.6), APBA3 (1.3), CDKN1C (2.1).
WNT signaling FRZB (3.9), FZD1 (1.3), FZD4 (1.7), FZD7 (1.5), WIF-1 (6.6), DKK1 (1.9), DKK2 (1.7), TCF3 (1.5), TCF7 (1.1), TCFL2 (1.2), TLE1 (1), DAB2 (1.9), CTBP2 (1).
WNT-repressed factors ACTN3(1.1), AKAP12 (1.1), CTSB (1.4), PLA2G7 (3.1), LTBP2 (1), DAB2 (1.9), FST (2.3), CLU (1.2), TCF3 (1.5), MEG3 (1.7), PPAP2B (1.6), LPL (1.3), ID4 (1), CDKN1C (2.1).
Interferon signaling IFNA5 (2.9), IFNA6 (4), IFNA7 (1.4), STAT2 (1.5), CIS4 (1), SSI-3 (1.6).
Inositol phospholipid signaling INPP4B (1.2), PIGB (1.2), PLCB4 (1), PLCE2 (1.4), KIAA0581 (2), GPLD1 (2.2), PIK3CD (1.2), NUDT4 (1.7), LOC51196 (1.7).
  1. Functional classification of some of the genes that are selectively upregulated ≥ 2 fold in α6+/MHCI- cells relative to α6+/MHCI+ cells (for the full list see Additional file 1). The numbers shown in parentheses are in log2 scale and are the highest scores for that gene.