Figure 7

Phylogenetic tree showing the relationship, based on amino acid sequence, of eight virB2 paralogs in the Ap genome. Four were transcribed only in ISE6 (APH_1131 – APH_1134), and two only in HL-60 and HMEC-1 (APH_1144 and APH_1145). No transcript from APH_1130 or APH_1136 was measured. The tick cell line associated paralogs are closely related to each other, while those transcribed in the human cell lines form a separate group and are less related to each other. The tree was constructed with PAUP 4.0 using neighbor-joining: absolute variation. Values shown in branches correspond to 2000 bootstraps analysis.