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Table 1 EST clones significantly up-regulated in resistant and susceptible rainbow trout strains 24 hours after Myxobolus cerebralis exposure using a Wilcoxon test.

From: Discovery of genes implicated in whirling disease infection and resistance in rainbow trout using genome-wide expression profiling

Strain

Gene

Accession

Fold Change

H

Ubiquitin-like protein 1*

CB499972

8.98

H

Ubiquitin-like protein 1*

CA064176

3.80

H

Interferon regulating factor 1*

CA063565

7.24

H

Interferon regulating factor 1*

CA058315

3.63

H

PPAR-α-interacting complex protein 285*

CA056844

7.88

H

Similar to interferon-inducible protein Gig2*

CA054168

5.82

H

Metallothionein B*

CB507722

4.36

H

Metallothionein B *

CB508872

3.08

H

Metallothionein B*

CA046225

2.72

H

Metallothionein B

CK990592

2.00

H

Metallothionein B*

CB510653

3.55

H

Interferon regulatory factor 7*

CB500977

4.36

H

Cyclin-dependent kinase 4 inhibitor B

CA044251

3.12

H

Cyclin-dependent kinase 4 inhibitor B

CB499959

2.66

H

Beta-2 microglobulin precursor

CN442516

2.51

H

Beta-2 microglobulin precursor

CB498391

2.23

H

Beta-2 microglobulin precursor

CB496576

2.12

H

Beta-2 microglobulin precursor

CB505897

2.04

H

Beta-2 microglobulin precursor

CA043324

2.02

H

Proteasome subunit beta type 8 precursor

CB496486

2.39

H

Interferon-induced 35 kDa protein homolog

CB493302

2.38

H

Haptoglobin precursor

CA038906

2.20

H

VHSV-induced protein

CB498971

2.07

H

Neighbor of COX-4

CB517140

2.01

H

Unknown

CA050082

2.71

H

Unknown

CA062379

2.70

H

Unknown

CB515535

2.41

TL

Ubiquitin-like protein 1*

CB499972

7.56

TL

Ubiquitin-like protein 1

CA064176

3.47

TL

Interferon regulating factor 1*

CA063565

4.81

TL

Interferon regulating factor 1

CA058315

2.80

TL

Interferon regulating factor 1

CA063863

2.55

TL

PPAR-alpha-interacting complex protein 285*

CA056844

3.31

TL

Similar to interferon-inducible protein Gig2

CA054168

3.20

TL

Similar to CC chemokine SCYA113

CB503743

2.26

TL

Unknown

CA062379

2.30

  1. H = Hofer (resistant strain); TL = Trout Lodge (susceptible strain); * = In addition to being significant using the Wilcoxon rank sum, these genes are also significant using the modified t-test employed in SAM. Q-values < 1% were considered significant for both tests.