Figure 2

Cellular responses after six hours exposure to L. plantarum. After continuous injection of L. plantarum WCFS1 for six hours into the proximal duodenum, proteins involved in fatty acid metabolism, cell motility and immune responses were modulated. Genes encoding proteins involved in fatty acid metabolism are in the upper left area of the image, those involved in cell motility (may include genes expressed in immune cells) are in the central area, and genes involved in innate and adaptive immune response are in the upper right area. Note the modulated ERK/MAPK/MKP-1 signalling pathway that extends into the nucleus.