Identification of the transcriptional response of human intestinal mucosa to Lactobacillus plantarum WCFS1 in vivo

Table 2 GenMAPP pathways affected by a 6-h exposure of duodenal mucosa to L. plantarum WCFS1

GO Name	Changed	Measured	Total
energy pathways	14	83	92
Cytoplasm	26	514	636
oxidoreductase activity	30	318	453
MHC class II receptor activity	5	11	31
tricarboxylic acid cycle	7	22	29
fatty acid beta-oxidation	5	12	13
electron transport	27	221	346
antigen presentation\, exogenous antigen	4	10	30
antigen presentation\, endogenous antigen	4	7	13
antigen processing\, exogenous antigen via MHC class II	4	10	30
antigen processing\, endogenous antigen via MHC class I	4	10	18
endoplasmic reticulum	26	235	271
Mitochondrion	29	365	464
cytochrome-c oxidase activity	5	16	27
Microsome	14	94	118
unspecific monooxygenase activity	6	23	23
lipid metabolism	9	104	129
Glycolysis	8	39	56
Cytosol	12	126	141
mitochondrial membrane	4	10	13
inner membrane	6	26	33
hydrogen ion transporter activity	3	26	33

Biological processes with relatively high numbers of gene reporters changed, based on the Gene Ontology (GO) database. The table shows the process title (GO name), the number of gene reporters changed changed (changed), measured with the microarrays (measured) and the total number of genes present in the pathway MAPP (total) (for detailed description of pathway selection, see Methods).

ISSN: 1471-2164