Table 3 Immune-related responses of human intestinal mucosal cells to L. plantarum WCFS1
component | function | regulation after 1 hr exposure | regulation after 6 hrs exposure |
|---|---|---|---|
IL-1 | interleukin-1 cytokine, induction immune responses |
| - |
IL-1R | receptor for interleukin-1 (IL-1) |
| - |
IF | complement factor I, serine protease, activator of complement pathway of innate immune response |
| - |
CFD (adipsin) | serine protease, activator of complement pathway of innate immune response |
| - |
C1R | serine protease, activator of complement pathway of innate immune response and GPCR 1 pathway |
| - |
C1S | serine protease, activator of complement pathway of innate immune response and GPCR 1 pathway |
| - |
C8G | part of antibacterial membrane attack complex (MAC) |
| - |
CD74 | TM receptor, antigen presentation, immune response and humoral defence | - |
|
CD93 | cell-surface glycoprotein, part of complement component 1, activator of macrophage and cellular adhesion |
| - |
HLA-A * | regulation of NK cell cytotoxicity | - |
|
HLA-C | endogenous antigen presentation | - |
|
HLA-E | immune response regulation, protection from NK cells | - |
|
HLA-G | regulatory/suppressive to T cells, cytokine tolerance | - |
|
HLA-DMA | antigen presentation, detection of microbes, CLIP release | - |
|
HLA-DMB | antigen presentation, detection of microbes, CLIP release | - |
|
HLA-DPA1 | antigen presentation derived from extracellular proteins | - |
|
HLA-DRA | antigen presentation derived from extracellular proteins |
|
|
HLA-DRB1 | antigen presentation derived from extracellular proteins | - |
|
