Figure 4
From: Altered gene expression in highly purified enterocytes from patients with active coeliac disease
Immunohistochemical detection of GJA4 in duodenal tissue. A: treated coeliac, nuclear staining of epithelial cells apparent while brush border staining absent; B: untreated coeliac (same patient as A), granular staining predominantly seen in cytoplasm of epithelial cells with increasing intensity towards brush border. Perinuclear staining visible in some cells although nuclear staining generally absent. C: normal control, showing perinuclear staining in the epithelium, similar to treated coeliac tissue, but with less frequent nuclear staining.