Altered gene expression in highly purified enterocytes from patients with active coeliac disease

BMC Genomics

Table 4 Microarray Experiment Patient Clinical Details

Patients	Sex	Age	Duodenal histology	Other histology, clinical information	Antibody status	Microarray number
Coeliac
1	Female	61	Grade 3a	none	tTG +	1
2	Female	45	Grade 3b	Barrett's oesophagus	tTG +	2
3	Female	22	Grade 1	none	tTG +	3
4	Female	31	Grade 3c	none	tTG +	4
5	Female	36	Grade 3c	mild reflux oesophagitis	tTG +	5
Control
6	Female	58	NDM	mild reflux oesophagitis	nk	1
7	Female	51	NDM	moderate reflux oesophagitis	tTG -	2
8	Female	25	NDM	none	nk	3
9	Female	30	NDM	superficial acute and chronic gastric inflammation	nk	4
10	Female	26	NDM	mild reflux oesophagitis	tTG -	5

Histology grade: 0 = normal; 1 = raised intraepithelial lymphocytes (IELs); 2 = increase in IELs with crypt hyperplasia; 3a = increase in IELs, crypt hyperplasia, mild villous atrophy; 3b = increase in IELs, crypt hyperplasia, marked villous atrophy; 3c = total villous atrophy [37]. NDM = normal duodenal mucosa. tTG, tissue transglutaminase antibody. nk, not known.

ISSN: 1471-2164