Figure 1From: Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumorsFrequency plot of copy number aberrations. Copy number changes of 20 breast tumors are illustrated using the Piecewise Constant Fit (PCF) method in the CGH-Explorer program. Amplified regions are marked red and deleted regions are marked green. The proportion of calls (all samples combined, and deletions and amplifications combined) was adjusted to 12% (for details see Methods). For every platform, specific high frequency (over 50%) small amplification or deletion peaks are visible (marked by stars *). For the Agilent platform: amplifications at 3p, and 20q, deletions at 4p, twice at 5q, and 9q; for the ROMA/NimbleGen platform: amplifications at 15q and deletions at 14q; the Illumina platform shows lower frequency peaks, but picked up a unique amplification at 14q not seen by the other platforms. (Indicated with blue bars are regions, for which additional information is provided in Figure 7 and in Additional files 8, 11, and 12. Further are indicated with brown bars regions, for which additional information is in Additional files 9 and 10).Back to article page