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Table 4 Average of inter-specific divergences in human SDs and chimpanzee SDs relative to genomic factors and rearrangements between human and chimpanzees.

From: The genomic distribution of intraspecific and interspecific sequence divergence of human segmental duplications relative to human/chimpanzee chromosomal rearrangements

HUMAN SD X-Chromosome Y-Chromosome Telomeres vs. rest of genome Centromeres vs. rest of genome Chromosome 19
  vs. Autosomes vs. Autosomes       
  SDs in autosomes SDs in the HSAX. SDs in autosomes SDs in the HSAY. SDs outside Telomeres SDs within Telomeres SDs outside Centromeres SDs within Centromeres SDs outside HSA19 SDs within HSA19
N 1303 109 1303 51 1052 251 742 310 714 28
Divergence 0.0238 0.0161 0.0238 0.0259 0.0233 0.026 0.0228 0.0247 0.0225 0.0285
P-value   < 0.001   0.087   < 0.001   < 0.001   0.001
CHIMP SD X-Chromosome Y-Chromosome Telomeres vs. rest of genome Centromeres vs. rest of genome Chromosome 19
  vs. Autosomes vs. Autosomes       
  SDs in autosomes SDs in the HSAX. SDs in autosomes SDs in the HSAY. SDs outside Telomeres SDs within Telomeres SDs outside Centromeres SDs within Centromeres SDs outside HSA19 SDs within HSA19
N 1415 110 1415 87 1224 191 789 435 779 10
Divergence 0.0222 0.0156 0.0222 0.0223 0.0217 0.0252 0.021 0.0231 0.0207 0.038
P-value   < 0.001   0.891   < 0.001   < 0.001   < 0.001
HUMAN SD Rearranged vs. SDs within vs.     
  Colinear chromosomes outside rearranged regions (excluding HSA2)     
  SDs in colinear chr. SDs in Rearranged chr. P-value SDs Outside inversions SDs inside inversions P-value     
N 267 447   280 112      
Divergence 0.0236 0.0219 0.01 0.0218 0.0219 0.934     
CHIMP SD Rearranged vs. SDs within vs.     
  Colinear chromosomes outside rearranged regions (excluding HSA2)     
  SDs in colinear chr. SDs in Rearranged chr. P-value SDs Outside inversions SDs inside inversions P-value     
N 256 523   312 160      
Divergence 0.0216 0.0203 0.025 0.0202 0.0199 0.693     
HUMAN SD Breakpoints vs.        
  inverted chromosomes        
  (excludingHSA2)        
  SDs in Rearranged chr. SDs in BKPs P-value        
N 370 22         
Divergence 0.0217 0.0242 0.136        
CHIMP SD Breakpoints vs.        
  inverted chromosomes        
  (excludingHSA2)        
  SDs in Rearranged chr. SDs in BKPs P-value        
N 441 31         
Divergence 0.0201 0.0194 0.552        
HUMAN SD SDs within vs. outside rearranged regions        
  (excluding breakpoints and HSA2)        
  SDs Outside inversions SDs inside inversions P-value        
N 264 106         
Divergence 0.0216 0.022 0.619        
CHIMP SD SDs within vs. outside rearranged regions        
  (excluding breakpoints and HSA2)        
  SDs Outside inversions SDs inside inversions P-value        
N 291 150         
Divergence 0.0202 0.0199 0.583        
HUMAN SD inversions (Newman et al. 2005) versus rest chromosomes        
  SDs Outside inversions SDs inside inversions P-value        
N 670 44         
Divergence 0.0227 0.0196 0.015        
CHIMP SD inversions (Newman et al. 2005) chromosomes        
  SDs Outside inversions SDs inside inversions P-value        
N 713 66         
Divergence 0.021 0.0183 0.004        
  1. Divergence is calculated as the number of substitution per site between the two duplication alignments.