Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate

BMC Genomics

Table 1 Differentially expressed genes involved in antioxidant defence in artesunate-treated cells

Gene ID	Description	ART 3 h	HS
PFI0925w	gamma-glutamylcysteine synthetase	1,41	+
PFE0605c	glutathione synthetase	0,94
PFL0595c	glutathione peroxidase	-0,95
PF11_0352	protein disulfide isomerase related protein	-0,89	-

Genes coding for proteins involved in antioxidant defence defined in [23].
Gene ID: identifier as found in PlasmoDB.
Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.
HS column: over (+) or under (-) expression.
Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].

ISSN: 1471-2164