Fractions of up- and downregulated genes in functional groups. Relative numbers of upregulated (red), downregulated (blue) and unregulated (yellow) genes categorized in GO biological process terms upon HAC1 overexpression (left panel) and DTT treatment (right panel). Shaded in black: regulated in both treatments. Upper panels: cut-off p-value < 0.05, lower panel cut-off p-value < 0.05 and FC > 1.5. The results of significance testing (Fisher's exact test) are given in additional file 4.