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Table 1 Characteristics of patients of the TRANSBIG validation series (n = 198), according to the 70-gene signature (GENE70), the 76-gene signature (GENE76), the Gene expression Grade Index (GGI) and the Adjuvant! Online (AOL) risk classifications.

From: Comparison of prognostic gene expression signatures for breast cancer

Signature GENE70 GENE76 GGI AOL
Number of patients Low-risk
(N = 66)
High-risk
(N = 132)
Low-risk
(N = 55)
High-risk
(N = 143)
Low-risk
(N = 69)
High-risk
(N = 129)
Low-risk
(N = 46)
High-risk
(N = 152)
Age         
   < 41 years 11 31 10 32 10 32 4 38
   41–50 years 33 67 24 76 33 67 33 67
   51–60 years 33 34 24 35 26 30 9 47
Size         
   T1ab (< 1 cm) 4 5 4 5 4 5 8 1
   T1c (1–2 cm) 24 35 17 42 25 34 21 38
   T2 (2–5 cm) 38 92 34 96 40 90 17 113
Tumor grade         
   Good differentiation 17 13 14 16 20 10 23 7
   Intermediate 42 41 21 62 44 39 23 60
   Poor differentiation 7 76 20 63 5 78 0 83
   Unknown 0 2 0 2 0 2 0 2
Estrogen receptors         
   Positive 63 71 41 93 65 69 46 88
   Negative 3 61 14 50 4 60 0 64