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Table 3 Multivariate Cox analyses for the 70-gene signature (GENE70), the 76-gene signature (GENE76) and the Gene expression Grade Index (GGI) risk classifications.

From: Comparison of prognostic gene expression signatures for breast cancer

  GENE70 GENE76 GGI
  HR
(95% CI)
p-value HR
(95% CI)
p-value HR
(95% CI)
p-value
Age (≤ or >50 years) 1.51 (0.82–2.79) 0.3 1.78 (0.97–3.25) 0.062 1.73 (0.94–3.16) 0.077
Tumor Size (≤ or >2 cm) 1.3 (0.72–2.5) 0.36 1.27 (0.68–2.37) 0.45 1.22 (0.65–2.29) 0.53
ER status 0.82 (0.43–1.6) 0.57 0.6 (0.31–1.17) 0.13 0.78 (0.4–1.51) 0.46
Grade 0.93 (0.34–2.53) 0.89 1.51 (0.53–4.28) 0.5 0.75 (0.27–2.08) 0.58
Risk according to the gene signature 7.1 (2.4–21) 4 × 10-4 3.39 (1.41–8.12) 6 × 10-3 6.42 (2.36–17.45) 3 × 10-4