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Figure 4 | BMC Genomics

Figure 4

From: Detection of genome-wide polymorphisms in the AT-rich Plasmodium falciparum genome using a high-density microarray

Figure 4

Genome browser displays (drawn in Canvas) showing SFP, mSFP and SNP from two genomic loci on chromosome 7. A. A genome browser window (~3 kb) showing expanded chromosome region covering pfcrt gene (top line) and predicted exons/introns of the pfcrt gene, SNP in PlasmoDB (blue circle), NIAID SNP (red diamonds), SFP from individual probe (light blue squares), mSFP (black squares) and all genomic probes covering the pfcrt gene. Color codes for the genomic probes are: green, probes in coding regions; purple, probes in noncoding regions; and yellow, probes spanning protein coding and noncoding regions. Note the mSFP matched well with those known SNP. B. An expanded region (500-bp window) from PF07_0028 showing distributions of PladmoDB SNP and array probe locations. Five of the seven PlasmoDB SNP (blue circle) in the intron were not covered by any probes. One SNP matched a mSFP call (black bars in multiple parasites), and another was covered by one probe and but was not called (filtered out because of single probe). The color codes for the genomic probes are the same as those in A; the labels are either SNP ID (blue circles) or probe ID (black and light blue bars).

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