Class | Name | Function | Y. enterocolitica | P. luminescens | Distribution among bacterial genera | Possible role in insect gut/hemolymph |
---|---|---|---|---|---|---|
Substrate transport | gltP/dctA (1) | glutamate-aspartate symport/transport of C4- dicarboxylates across the membrane | 0310 (gltP)/4067 (dctA) | dctA (Plu3205) | ubiquitous | uptake of peptides following protease activity |
 | - (1) | permease | YE3697 | Plu4591 | ubiquitous | unknown |
 | uhpABC (1) | hexose phosphate transport | YE4089-4087 | Plu0815-0813 | ubiquitous | exploitation of carbon sources |
 | mgtC (1) | Mg2+ transport ATPase protein | YE2586 | Plu1843 | ubiquitous | virulence factor in Salmonella |
 | hemHFRS (3, 4) | hemin storage | YE2481-2484 | no homologue | ubiquitous | storage of excess hemin |
 | irp1/irp2 (7) | yersiniabactin biosynthesis | YE2617/YE2618 | Plu2320/Plu2321 | ubiquitous | iron acquisition |
 | fepG (5) | iron-siderophore transport | YE3620 | Plu4625 | ubiquitous | iron acquisition |
Membrane proteins | - (1) | unknown | YE1324 | no homologue | ubiquitous | unknown |
 | ompN homologue (1) | pore formation | YE2463 | Plu1751 | ubiquitous | osmolarity |
 | crcB (1) | unknown | YE0964 | Plu1290 | ubiquitous | unknown |
 | - (1) | unknown | YE2063 | no homologue | Yersinia, Burkholderia, Pseudomonas | unknown |
 | - (1) | hypothetical membrane protein | YE2063 | no homologue | Yersinia, Burkholderia, Pseudomonas, | unknown |
 | rfb (9) | synthesis of LPS O antigen | YE3072-3087 | Plu4817-4819, Plu4824, Plu4831 | ubiquitous | blocking the access of bile salts and complement to the outer membrane |
 | - (1) | putative lipoprotein | YE2793 | no homologue | species-specific | unknown |
Substrate utilization | urease (1, 3, 10) | urea amidohydolase | YE0951-0958 | Plu2171-2177; transporter missing | ubiquitous | pH adaptation, ammoniak degradation |
 | hutH (1) | histidine ammonia-lyase | YE3021/YE4094 | Plu3192 | ubiquitous | histidine utilization |
 | prtA (6) | alkaline metalloprotease | YE4052 | Plu0655 | Yersinia, Serratia, Pseudomonas, Erwinia | bioconversion |
 | glgB (1) | 1,4-a glucan branching enzyme | YE4013 | no homologue | ubiquitous | storage of surplus primary carbohydrates |
Regulation | arcAB (1) | TCS controlling the response to respiratory conditions | YE0595 | Plu0562 | ubiquitous | (virulence) regulation during anaerobic growth |
 | - (1) | putative transcription regulatory protein | YE1436 | Plu2862 | Yersinia | unknown |
 | - (1) | EAL domain; hypothetical | YE4063 | no homologue | Yersinia, Shigella, Escherichia | regulation of virulence via c-di-GMP |
 | - (1) | EAL domain; hypothetical | YE1324 | no homologue | Yersinia, Shigella, Escherichia, Vibrio | regulation of virulence via c-di-GMP |
 | yenI/yenR (yspI/yspR) (3) | N-acylhomoserine lactone synthase YenI/transcriptional regulator YenR | YE1600/YE1599 | no homologue | Sodalis, Serratia, Erwinia, Aeromonas, Pectobacterium, Pseudomonas, Agrobacterium, | quorum sensing contributing to the regulation of virulence gene expression |
Virulence factors | srfA (1) | putative virulence factor, ssrAB activated in S. typhimurium | YE2057 | no homologue | Yersinia, Salmonella, Pseudomonas, Enterobacter | unknown |
 | fhaC (1) | hemolysin secretion | YE0480 | no homologue | Yersinia, Burkholderia, Pseudomonas, Bordetella, Haemophilus | cytolytic effect on immunocytes and hemolytic effect on blood cells |
 | yst (2) | heat-stable enterotoxin | not annotated | no homologue | Yersinia | release of nutrients from gut cells |
 | tcdA, tcdB and tccC-like elements (1) | insecticidal toxin complex | tc-PAIYe | numerous loci | Yersinia, Xenorhabdus, Serratia | cytotoxic activity against insect tissue |
 | phlA/B (5) | hemolysin secretion | YE2407/YE2408 | Plu0316/Plu0317 | ubiquitous | cytolytic effect on immunocytes and hemolytic effect on blood cells |
 | invE (11) | adhesion/invasion | YE3547 | no homologue | ubiquitous | colonization of insect gut |
 | ysa (12) | T3SS | see Fig. 5 | see Fig. 5 | Yersinia, Burkholderia, Erwinia, Xanthomonas, Salmonella | colonization of insect gut |
 | fleABC etc.(1) | flagellar genes | Flag-1 genes | Flag-1 genes | ubiquitous | motility |
 | yplA (8) | Phospholipase | YE1005 | Plu3370 | Yersinia, Serratia, Xanthomonas | survival within the insect host |