Skip to main content

Table 10 Top ten gender-dependent cancer-related genes that have the greatest fold change due to hepatocyte RXRα deficiency.

From: Hepatocyte RXRalpha deficiency in matured and aged mice: impact on the expression of cancer-related hepatic genes in a gender-specific manner

Male vs. Female (6 month old mice)
Genes in C Folds (WT) Folds (KO) Fold change due to RXRα deficiency
MYC 33.49 5.52 6.07
CDKN1A 27.04 5.03 5.38
CYP17A1 -32.26 -10.32 3.13
BTG2 10.53 3.48 3.03
HSPA1B 23.96 8.35 2.87
ABCB1 -8.77 -19.23 0.46
B4GALNT1 -2.73 -6.06 0.45
PTP4A3 -4.33 -10.67 0.41
CXCL2 2.89 8.40 0.34
HSPB1 6.40 19.48 0.33