Table 4 Fold changes of the mRNA levels of the metastasis-related genes in male and female hepatocyte RXRα-deficient mouse livers.
6 month male mice (KO vs. WT) | 6 month female mice (KO vs. WT) | ||||
|---|---|---|---|---|---|
Name | Fold Change | Function | Name | Fold Change | function |
ARHGDIB | -2.05 | anti-metastasis | BRMS1 | -2.16 | anti-metastasis |
KRT18 | -2.15 | anti-metastasis | CD36 | -2.88 | anti-metastasis |
CD36 | -2.16 | anti-metastasis | MYO10 | 2.63 | pro-metastasis |
KRT19 | -2.43 | anti-metastasis | ROCK1 | -2.24 | pro-metastasis |
THBS1 | -7.11 | anti-metastasis | CTTN | -2.88 | pro-metastasis |
SERPINE1 | -23.48 | anti-metastasis | ITGA6 | -3.64 | pro-metastasis |
CAV1 | 2.86 | pro-metastasis | |||
FN1 | 2.67 | pro-metastasis | |||
ID2 | 2.65 | pro-metastasis | |||
DDEF1 | 2.52 | pro-metastasis | |||
CLCA1 | 2.33 | pro-metastasis | |||
S100A10 | -2.09 | pro-metastasis | |||
ADAM12 | -2.12 | pro-metastasis | |||
CNN2 | -2.16 | pro-metastasis | |||
PLAUR | -2.25 | pro-metastasis | |||
PLAT | -2.30 | pro-metastasis | |||
NEDD9 | -2.39 | pro-metastasis | |||
SPP1 | -2.75 | pro-metastasis | |||
CTGF | -2.90 | pro-metastasis | |||
VIM | -3.25 | pro-metastasis | |||
LGALS7 | -3.79 | pro-metastasis | |||
EPHA2 | -4.71 | pro-metastasis | |||
24 month male mice (KO vs. WT) | 24 month female mice (KO vs. WT) | ||||
Name | Fold Change | Function | Name | Fold Change | function |
TIMP4 | 4.07 | anti-metastasis | DDR1 | -2.20 | anti-metastasis |
ANK3 | 2.07 | anti-metastasis | TFF3 | 11.22 | pro-metastasis |
LGALS3 | 2.00 | anti-metastasis | ADAM15 | 3.38 | pro-metastasis |
TFF3 | 4.05 | pro-metastasis | MMP9 | 2.49 | pro-metastasis |
CTGF | 2.22 | pro-metastasis | ITGB1 | 2.48 | pro-metastasis |
MT1E | 2.19 | pro-metastasis | CSF2RB | 2.32 | pro-metastasis |
CAV1 | 2.15 | pro-metastasis | FOXM1 | 2.13 | pro-metastasis |
PLAUR | 2.03 | pro-metastasis | MYO6 | -4.70 | pro-metastasis |
PTP4A3 | -2.55 | pro-metastasis | |||