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Table 1 Estimated STR overrepresentation in disease-related genes, relative to the proportion of STR in reference genes.

From: Short Tandem Repeats in Human Exons: A Target for Disease Mutations

Gene set #Genes STR overrepresentation a P-value
Human genes
Reference set 11210 - -
All diseases 2095 7.0 % [4.6, inf] 2.1 × 10-7
Leukaemia 70 28.3 % [15.2, inf] 1.7 × 10-4
Cancers 151 17.5 % [8.8, inf] 3.3 × 10-4
Immune system diseases 52 16.5 % [3.0, inf] 2.1 × 10-2
Mouse genes
Reference set 17077 - -
Cancers 294 12.1 % [5.3, inf] 7.6 × 10-4
Postnatal lethality 764 25.7 % [21.6, inf] <10-12
  1. a 95% confidence intervals are in brackets.