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Table 2 Selected Enriched Gene Ontology Categories

From: Transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in liver: Comparison of rat and mouse

GO ID Rat Mouse Common GO Term
GO:0006118 3.33E-04 3.43E-01 8.43E-03 electron transport
GO:0006984 1.01E+00 1.00E+00 9.67E-03 ER-nuclear signaling pathway
GO:0006986 1.02E+00 1.01E+00 1.10E-02 response to unfolded protein
GO:0005792 2.89E-01 7.64E-01 1.30E-02 microsome
GO:0020037 7.99E-01 9.21E-01 2.61E-02 heme binding
GO:0016491 1.00E-04 2.71E-03 4.02E-02 oxidoreductase activity
GO:0005832 9.99E-01 2.82E-02 1.01E+00 chaperonin-containing T-complex
GO:0006412 1.04E+00 1.11E-04 1.02E+00 translation
GO:0030529 1.04E+00 1.00E-04 1.02E+00 ribonucleoprotein complex
GO:0030151 1.01E+00 1.81E-02 1.03E+00 molybdenum ion binding
GO:0008610 7.20E-02 5.74E-01 1.05E+00 lipid biosynthetic process
GO:0044255 1.18E-02 3.72E-02 1.15E+00 cellular lipid metabolic process
  1. Genes differentially expressed in each species were selected at padjusted < 0.01 using linear-modeling analysis. The set of genes whose mRNA levels were altered by TCDD in only mice, only rats, or in both species were separately subjected to Gene Ontology enrichment analysis to identify specific pathways or functions modulated. A selection of enriched GO terms is shown. The numeric values are false-discovery rates estimated by 1,000 permutations of the input data. Only a subset of GO categories is shown. Bold text indicates those categories significant at a 10% false-discovery rate.