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Table 3 Selected UCR Motifs

From: Comparative genomics of small RNA regulatory pathway components in vector mosquitoes

     Proportion of UCRs with Motif Median Motifs per UCR
Motif FET p value BH Enriched over genome? miRNA siRNA PIWI miRNA siRNA PIWI
NFkB2 not sig.^ not sig. No 0.188 0.250 0.100 1.0 1.0 1.0
NFkB4 not sig. not sig. No 0.313 0.438 0.460 1.0 1.0 1.0
NFkB7* not sig. not sig. No 0.188 0.375 0.280 1.0 1.0 1.0
BRC_Z1 not sig. not sig. No 0.813 0.313 0.540 1.0 1.0 1.0
BRC_Z2 not sig. not sig. No 0.563 0.688 0.620 1.0 1.0 1.0
Pathway-specific        miRNA siRNA PIWI
M19 (miRNA) not sig. not sig. Yes 0.188 0.100 0.033 4.5 1 1
M21 (miRNA) not sig. not sig. Yes 0.219 0.100 0.067 2 2 1
M24 (siRNA) not sig. not sig. Yes 0.063 0.400 0.200 1 14 1
M26 (siRNA) not sig. not sig. Yes 0.031 0.250 0.033 2 3 2
M30 (PIWI) not sig. not sig. Yes 0.000 0.000 0.060 NA NA 5
Species-Specific     Aae Aga Cpi Aae Aga Cpi
M1 (Aedes) not sig. not sig. Yes 0.188 0.100 0.033 1.5 1.5 1
M2 (Aedes) not sig. not sig. Yes 0.219 0.100 0.067 2 2 1
M3 (Aedes) not sig. not sig. Yes 0.094 0.000 0.033 9 NA 1
M7 (Anopheles)# not sig. not sig. Yes 0.063 0.400 0.200 10.5 1.5 1
M8 (Anopheles) # not sig. not sig. Yes 0.031 0.250 0.033 10 1 1
M9 (Anopheles) < 0.001 0.002 No 0.000 0.400 0.300 NA 6 1
M12 (Culex)+ not sig. not sig. Yes 0.031 0.000 0.067 1 NA 21
M13 (Culex)+ not sig. not sig. Yes 0.031 0.000 0.067 1 NA 21
M17 (Culex) < 0.001 0.002 No 0.094 0.100 0.533 1 1 1
  1. "^", see Additional File 4 for details. "*", for NFkB7 only, significance scores were based on the presence of 2 or more hits per UCR. "#", enriched in an siRNA pathway specific manner. "+", enriched in an miRNA pathway specific manner. "BH", Benjamini-Hochberg test, cut-off = 0.05. "FET", Fisher's Exact test, cutoff = 0.01. "NA", not applicable. "Aae", Ae. aegypti, "Aga", An. gambiae, "Cpi", Cx. pipiens.