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Table 3 Cross-species overlap of single genes underlying specific GO-terms

From: Cross-species comparison of biological themes and underlying genes on a global gene expression scale in a mouse model of colorectal liver metastasis and in clinical specimens

 

Human

Murine

Overlap

 

No.

No.

No.

%

Secondary meatabolism

Lipid metabolism

59 ± 5.7

63.5 ± 2.1

9.5 ± 2.1

16.1

Nitrogen compound metabolism

53.5 ± 10.6

24 ± 1.4

9.5 ± 2.1

17.8

Immune response

Innate immune response

10.5 ± 2.1

18 ± 0

5 ± 1.4

47.6

Antigen presentation

6 ± 0

12 ± 2.8

2 ± 0

33.3

Invasion

Cell Adhesion

23 ± 4.2

40.5 ± 3.5

2 ± 1.4

8.4

Extracellular Matrix

20 ± 4.2

21.5 ± 2.1

3 ± 1.4

15

  1. Upper three GO-terms from both liver compartments, lower three GO-terms from human liver invasion and murine tumor invasion. Overlaps as total number and in percent of human genes. Experiments in duplicates.