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Figure 2 | BMC Genomics

Figure 2

From: The conservation pattern of short linear motifs is highly correlated with the function of interacting protein domains

Figure 2

Comparison of conservation scores and SH2 selectivity values between SH2 binding and non-binding Tyr-SLiMs in 11 highly studied RTKs. (A) SH2 binding Tyr-SLiMs are significantly more conserved than those that do not bind to SH2 domains (p < 0.0001, Mann-Whitney test). (B) Percentage of SLiMs that have different SH2 selectivity values in binding and non-binding groups.

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BMC Genomics

ISSN: 1471-2164

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