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Table 1 Classifications of fingerprints involved in insertion/deletion and truncation events.

From: Splice-mediated Variants of Proteins (SpliVaP) – data and characterization of changes in signatures among protein isoforms due to alternative splicing

Top-level PRINTS classifications of fingerprints No. of observed events* affecting
  the whole fingerprint& some of the constituent motifs of the fingerprint$
  Type A – insertion/
deletion of a
'complete' fingerprint
Type C – insertion/
deletion of a
'partial' fingerprint
Type B – truncation
of a 'complete' to
'partial' fingerprint
Type D – fingerprint is
partial in both the
isoforms and possess differing
number of constituent motifs
Receptors 61 (23%) 23 (8%) 159 (62%) 13 (5%)
  64 (22%) 33 (11%) 153 (54%) 33 (11%)
Enzymes: Hydrolases 11 (9%) 4 (3%) 90 (79%) 8 (7%)
  13 (10%) 2 (1%) 97 (73%) 19 (14%)
Transport proteins:others 51 (27%) 15 (7%) 100 (53%) 22 (11%)
  27 (19%) 21 (15%) 77 (55%) 15 (10%)
Enzymes: Oxidoreductases 17 (18%) 11 (11%) 39 (41%) 27 (28%)
  11 (10%) 19 (18%) 40 (38%) 34 (32%)
Enzymes: Transferases 13 (14%) 3 (3%) 69 (78%) 3 (3%)
  17 (18%) 5 (5%) 63 (68%) 7 (7%)
Structural proteins 26 (15%) 12 (7%) 107 (62%) 26 (15%)
  13 (14%) 6 (6%) 49 (55%) 20 (22%)
RNA- or DNA-associated proteins 17 (15%) 3 (2%) 67 (62%) 20 (18%)
  17 (23%) 2 (2%) 44 (60%) 10 (13%)
PRINTS 'Domains' signatures 20 (36%) 13 (23%) 21 (38%) 1(1%)
  26 (52%) 4 (8%) 17 (34%) 3 (6%)
Cytokines and growth factors 4 (14%) 2 (7%) 17 (62%) 4 (14%)
  6 (18%) 3 (9%) 22 (66%) 2 (6%)
Protein secretion and chaperones 0 (0%) 2 (14%) 8 (57%) 4 (28%)
  0 (0%) 6 (26%) 11 (47%) 6 (26%)
  1. *, Events of same insertion/deletion type involving fingerprint members of a PRINTS classification observed among multiple pairs of isoforms from a gene are counted as one. Per every type of insertion/deletion event, the observed numbers involving the five top scoring fingerprint PRINTS classification are underlined. In brackets are given values on what fraction of events involving the PRINTS classification is of the given insertion/deletion type – values > = 35% are in bold; values < = 15% are in italics. Values for Vega data set are given in line 1 and values for ASD data set are given in line 2 in every row.
  2. &, A fingerprint seen as either 'complete' (with all the constituent motifs) or 'partial' (with only some of the constituent motifs) in an isoform is deleted in the other isoform.
  3. $, Some of the constituent motifs of a fingerprint ('complete' or 'partial') in an isoform are deleted in the other isoform.