Table 1 Classifications of fingerprints involved in insertion/deletion and truncation events.
Top-level PRINTS classifications of fingerprints | No. of observed events* affecting | |||
|---|---|---|---|---|
the whole fingerprint& | some of the constituent motifs of the fingerprint$ | |||
Type A – insertion/ deletion of a 'complete' fingerprint | Type C – insertion/ deletion of a 'partial' fingerprint | Type B – truncation of a 'complete' to 'partial' fingerprint | Type D – fingerprint is partial in both the isoforms and possess differing number of constituent motifs | |
Receptors | 61 (23%) | 23 (8%) | 159 (62%) | 13 (5%) |
64 (22%) | 33 (11%) | 153 (54%) | 33 (11%) | |
Enzymes: Hydrolases | 11 (9%) | 4 (3%) | 90 (79%) | 8 (7%) |
13 (10%) | 2 (1%) | 97 (73%) | 19 (14%) | |
Transport proteins:others | 51 (27%) | 15 (7%) | 100 (53%) | 22 (11%) |
27 (19%) | 21 (15%) | 77 (55%) | 15 (10%) | |
Enzymes: Oxidoreductases | 17 (18%) | 11 (11%) | 39 (41%) | 27 (28%) |
11 (10%) | 19 (18%) | 40 (38%) | 34 (32%) | |
Enzymes: Transferases | 13 (14%) | 3 (3%) | 69 (78%) | 3 (3%) |
17 (18%) | 5 (5%) | 63 (68%) | 7 (7%) | |
Structural proteins | 26 (15%) | 12 (7%) | 107 (62%) | 26 (15%) |
13 (14%) | 6 (6%) | 49 (55%) | 20 (22%) | |
RNA- or DNA-associated proteins | 17 (15%) | 3 (2%) | 67 (62%) | 20 (18%) |
17 (23%) | 2 (2%) | 44 (60%) | 10 (13%) | |
PRINTS 'Domains' signatures | 20 (36%) | 13 (23%) | 21 (38%) | 1(1%) |
26 (52%) | 4 (8%) | 17 (34%) | 3 (6%) | |
Cytokines and growth factors | 4 (14%) | 2 (7%) | 17 (62%) | 4 (14%) |
6 (18%) | 3 (9%) | 22 (66%) | 2 (6%) | |
Protein secretion and chaperones | 0 (0%) | 2 (14%) | 8 (57%) | 4 (28%) |
0 (0%) | 6 (26%) | 11 (47%) | 6 (26%) | |