Table 2 Percentage nucleotide (nts) and amino acid (aa) identity amongst domains of the mycolactone PKS from pMUM001 and pMUM002
From: Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones
| Â | pMUM001 | pMUM002 | Interspecies | |||
|---|---|---|---|---|---|---|
Domain (nts/aa) | nts | aa | nts | aa | nts | aa |
Ketosynthase-load (1149/383) | 100 | 100 | 100 | 100 | 99.6 | 98.7 |
Ketosynthase (1260/419) | 98.9 | 97.3 | 99.1 | 97.8 | 98.6 | 96.7 |
Acyltransferase-I (1056/352) | 100 | 100 | 100 | 100 | 99.8 | 99.7 |
Acyltransferase-II (999/333) | 100 | 100 | 100 | 100 | 99.2 | 99.1 |
Acyltransferase-III (1056/352) | 99.9 | 100 | 100 | 100 | 99.8 | 99.7 |
Dehydratase (465/155) | 98.7 | 96.1 | 99.3 | 99.3 | 98.3 | 98.7 |
Enoylreductase (948/316) | 100 | 100 | 100 | 100 | 100 | 100 |
Ketoreductase A (528/176) | 100 | 100 | 100 | 100 | 100 | 100 |
Ketoreductase B (540/180) | 99.6 | 98.9 | 99.4 | 98.3 | 98.7 | 97.2 |
Acyl carrier protein-I (210/70) | 95.7 | 95.7 | 98.6 | 100 | 95.2 | 95.7 |
Acyl carrier protein-II (210/70) | 100 | 100 | 99.5 | 98.6 | 99.1 | 97.1 |
Acyl carrier protein-III (210/70) | 98.6 | 98.6 | 97.6 | 95.7 | 96.2 | 94.3 |
Chromosomal | Â | Â | Â | Â | 99.6* | 99.4 |
Plasmid (other) | Â | Â | Â | Â | 99.7 | 99.3 |