TY - JOUR AU - Baertsch, Robert AU - Diekhans, Mark AU - Kent, W. James AU - Haussler, David AU - Brosius, Jürgen PY - 2008 DA - 2008/10/08 TI - Retrocopy contributions to the evolution of the human genome JO - BMC Genomics SP - 466 VL - 9 IS - 1 AB - Evolution via point mutations is a relatively slow process and is unlikely to completely explain the differences between primates and other mammals. By contrast, 45% of the human genome is composed of retroposed elements, many of which were inserted in the primate lineage. A subset of retroposed mRNAs (retrocopies) shows strong evidence of expression in primates, often yielding functional retrogenes. SN - 1471-2164 UR - https://doi.org/10.1186/1471-2164-9-466 DO - 10.1186/1471-2164-9-466 ID - Baertsch2008 ER -