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Table 1 Downregulated genes in the ATRX-null forebrain at E13.5 and P0.5.

From: The SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in the mouse genome

   Chromosome   
Gene Description Mouse Human Fold Change Genbank
E13.5 Downregulated Genes
IMAGE:354942 Similar to dehydrogenase/reductase (SDR family) X chromosome ( Dhrsxy ) 1 4 X/Y PAR -4.81 W45978
Csf2ra Colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 19 X/Y PAR -3.05 BM941868
Vit Vitrin 17 2 -2.74 AF454755
Shox2 Short stature homeobox 2 3 X/Y PAR -2.73 AV332957
Tcf7l2 Transcription factor 7-like 2, T-cell specific, HMG-box 19 10 -2.72 BB175494
Gbx2 Gastrulation brain homeobox 2 1 2 -2.55 L39770
IMAGE:3326212 Similar to Arylsulfatase E ( Arse ) 1 - X/Y -2.21 BE457721
Syt13 Synaptotagmin 13 2 11 -2.19 BB244585
Cd99 CD99 antigen 4 X/Y PAR -2.09 AK004342
Nxph1 Neurexophilin 1 6 7 -1.92 BB274960
Neurod4 Neurogenic differentiation 4 10 12 -1.86 NM_007501
Nxph2 Neurexophilin 2 2 2 -1.86 BB169128
Peg10 Paternally expressed 10 6 7 -1.86 BG076799
RIKEN:1810009N02 Similar to Asmtl (acetylserotonin O-methyltransferase-like) 1 - X/Y PAR -1.81 AK007409
Wif1 Wnt inhibitory factor 1 10 12 -1.81 BC004048
P0.5 Downregulated Genes
Csf2ra Colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 19 X/Y PAR -7.14 BM941868
Nr4a2 Nuclear receptor subfamily 4, group A, member 2 2 2 -3.33 NM_013613
IMAGE:354942 Similar to Dhrsxy (dehydrogenase/reductase (SDR family) X chromosome 1 4 X/Y PAR -3.33 W45978
IMAGE:5656844 Unknown EST - - -2.86 BI320076
Met Met proto-oncogene 6 7 -2.78 BG060788
Cd99 CD99 antigen 4 X/Y PAR -2.22 AK004342
Dsc3 Desmocollin 3 18 18 -2.22 NM_007882
Mbp Myelin basic protein 18 18 -2.17 AI323506
Cbln4 Cerebellin 4 precursor protein 2 20 -2.08 AV343573
EST Unknown EST - - -2.08 BI202412
Trpc4 Tansient receptor potential cation channel, subfamily C, member 4 3 13 -2.04 BB271442
RIKEN:1810009N02 Similar to Asmtl (acetylserotonin O-methyltransferase-like) 1 - X/Y PAR -2.00 AK007409
  1. 1By BLASTn
  2. cRNA was generated from total forebrain RNA from three pairs of littermate-matched ATRX-null and wild type forebrain tissue and hybridized to an Affymetrix Mouse Genome 430 2.0 Array. Data was analyzed using GeneSpring. Probesets were filtered by fold change (1.8 fold at P0.5, 2 fold at E13.5) and confidence, P < 0.05, and duplicate genes were removed. Ancestral PAR genes are highlighted in grey.