Skip to main content

Advertisement

Table 3 Genes showing overlapping up- or down-regulation in iDCs after treatment with [BF/S+L/Ep] or cichoric acid

From: Genomics and proteomics of immune modulatory effects of a butanol fraction of echinacea purpurea in human dendritic cells

Genes up-regulated Genebank Fold Change in Treatment with [BF/S+L/Ep] (From 23.9 to 2.7-fold) Fold Change in Treatment with Cichoric Acid (From 14 to 3.1-fold)
adaptor-related protein complex 4 NM_007077 23.91 14.10
secreted frizzled-related protein 1 NM_003012 10.17 10.11
cholinergic receptor NM_000745 9.95 6.02
chorea acanthocytosis AB023203 9.91 9.56
tripartite motif-containing 45 NM_025188 8.34 8.26
zinc finger protein (ZFD25) NM_016220 5.27 5.35
SUMO-1-specific protease NM_015571 5.02 4.56
nuclear respiratory factor 1 NM_005011 4.97 3.39
pleckstrin homology-like domain NM_007350 4.79 3.36
protein phosphatase 2 NM_004576 4.56 6.75
chromosome 19 open reading frame 2 NM_003796 3.91 3.27
SMC5 structural maintenance of chromosomes 5-like 1 (yeast) NM_015110 3.87 5.78
myeloid/lymphoid or mixed-lineage leukemia NM_004641 3.70 5.34
aryl hydrocarbon receptor interacting protein-like 1 NM_014336 3.60 3.70
left-right determination, factor B NM_020997 3.53 4.14
ATP-binding cassette, sub-family A NM_005502 3.35 5.36
RBP1-like protein NM_016374 3.07 3.26
solute carrier family 26, member 10 NM_133489 2.89 3.05
insulin induced gene 1 NM_005542 2.87 3.12
ceroid-lipofuscinosis, neuronal 8 NM_018941 2.72 3.10
Genes down-regulated Gene bank (From 0.08 to 0.38-fold) (From 0.13 to 0.4-fold)
Interferon-inducible protein p78 (mouse) NM_002462 0.09 0.13
Interferon-inducible protein 44 NM_006417 0.16 0.16
Interferon, alpha-inducible protein (clone IFI-15K) NM_005101 0.19 0.20
Mitochondrial ribosomal protein S14 NM_022100 0.27 0.31
2'-5'-oligoadanylate synthetase 2, 69/71 kDa NM_016817 0.27 0.24
Myxovirus (influenza virus) resistance 2 (mouse) NM_002463 0.29 0.30
XIAP associated factor-1 NM_017523 0.30 0.33
SP110 nuclear body protein NM_080424 0.33 0.35
Signal transducer and activator of transcription 1, (91 kDa) NM_007315 0.33 0.29
zinc finger antiviral protein NM_020119 0.34 0.36
Solute carrier family 35 NM_012243 0.36 0.38
  1. Human immature DCs were treated for 24 h with test samples and assayed for differential gene expression.