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Figure 6 | BMC Genomics

Figure 6

From: Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays

Figure 6

Relative magnitude of LR changes in diploid and tetraploid backgrounds. The lighter signal trace represents loss of the entire chromosome 10 in C172 where an LR of 0 corresponds to a CN of 2. In this case, a CN loss of 1 produces a LR of -0.4. In C72 where the background is largely tetraploid (the dark signal trace), a single copy loss (i.e., from CN of 4 to CN of 3) in the q-arm of chromosome 10 results in a decrease of the LR to only -0.15.

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