Figure 6From: Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping ArraysRelative magnitude of LR changes in diploid and tetraploid backgrounds. The lighter signal trace represents loss of the entire chromosome 10 in C172 where an LR of 0 corresponds to a CN of 2. In this case, a CN loss of 1 produces a LR of -0.4. In C72 where the background is largely tetraploid (the dark signal trace), a single copy loss (i.e., from CN of 4 to CN of 3) in the q-arm of chromosome 10 results in a decrease of the LR to only -0.15.Back to article page